A novel implanted device to wirelessly record and analyze continuous intracranial canine EEG

作者：Davis Kathryn A^*; Sturges Beverly K; Vite Charles H; Ruedebusch Vanessa; Worrell Gregory; Gardner Andrew B; Leyde Kent; Sheffield W Douglas; Litt Brian

来源：Epilepsy Research, 2011, 96(1-2): 116-122.

DOI：10.1016/j.eplepsyres.2011.05.011

• Intracranial
• EEG
• Canine
• Epilepsy device

We present results from continuous intracranial electroencephalographic (iEEG) monitoring in 6 dogs with naturally occurring epilepsy, a disorder similar to the human condition in its clinical presentation, epidemiology, electrophysiology and response to therapy. Recordings were obtained using a novel implantable device wirelessly linked to an external, portable real-time processing unit. We demonstrate previously uncharacterized intracranial seizure onset patterns in these animals that are strikingly similar in appearance to human partial onset epilepsy. We propose: (1) canine epilepsy as an appropriate model for testing human antiepileptic devices and new approaches to epilepsy surgery, and (2) this new technology as a versatile platform for evaluating seizures and response to therapy in the natural, ambulatory setting.

• 出版日期2011-9