Determinants of societal costs in Alzheimer's disease: GERAS study baseline results

作者：Dodel Richard; Belger Mark; Reed Catherine^*; Wimo Anders; Jones Roy W; Happich Michael; Argimon Josep M; Bruno Giuseppe; Vellas Bruno; Maria Haro Josep

来源：Alzheimer's and Dementia, 2015, 11(8): 933-945.

DOI：10.1016/j.jalz.2015.02.005

• Alzheimer's disease
• Cost of illness
• Dementia
• Health care costs
• Factors

Background: To identify the main factors associated with societal costs of Alzheimer's disease (AD) in community-dwelling patients across three European countries.
Methods: Baseline cost data from a prospective, observational study were used. Assessments included patients' cognition, activities of daily living (ADLs) and behavioral symptoms, and caregiver burden. Cost calculations (2010) from the societal perspective were based on patient/caregiver resource use. Generalized linear models estimated factors associated with costs.
Results: Mean monthly costs per patient differed for France (sic1881), Germany (sic2349), and the UK (sic2016), with informal care costs accounting for 50% to 61%. Independent factors associated with costs across all countries were ADL total score, patient living arrangements, caregiver working status, and caregiver burden (all P < .05). Additional factors were significant for the pooled cohort or individual countries.
Conclusions: Several patient and caregiver factors, including factors associated with informal care, should be included when evaluating care options for patients with AD.

• 出版日期2015-8