A Tetraphenylethene Luminogen-Functionalized Gemini Surfactant for Simple and Controllable Fabrication of Hollow Mesoporous Silica Nanorods with Enhanced Fluorescence

作者：Yan, Saisai; Gao, Zhinong^*; Xia, Yan; Liao, Xueming; Chen, Yifan; Han, Jia; Pan, Chenchen; Zhang, Yingfang

来源：Inorganic Chemistry, 2018, 57(21): 13653-13666.

DOI：10.1021/acs.inorgchem.8b02252

• STEP SYNTHESIS
• DRUG-DELIVERY
• NANOPARTICLES
• NANOSPHERES
• BEHAVIOR
• SPHERES
• DESIGN

Nanoparticles that possess unique structures and properties are highly desired in the production of multifunctional materials because of their combinational performance. In this study, a facile and effective fabricating strategy is developed to controllably prepare fluorescent hollow mesoporous silica nanorods via the cetyltrimethylammonium bromide (CTAB) and tetraphenylethene (TPE) luminogen-functionalized gemini surfactant (C-TPE-C-6-C-TPE) guided dual-templating approach. Because of its unique chemical structure, water solubility, surface activity, and fluorescent properties, the designed C-TPE-C-6-C-TPE will not only provide an anchored fluorophore for silica nanoparticles but also serve as an intimate partner of CTAB to regulate their construction in the structure-directing process. By properly tuning the molar ratio of CTAB/C-TPE-C-6-C-TPE, the shape controlled aggregation-induced emission hollow mesoporous silica nanoparticles (AIE-MSNs) can be prepared directly, producing two kinds of silica nanorods (AIE-MSNs-15 and A.T.E-MSNs-7). In particular, the incorporated bulky TPE luminogens will not only endow AIE-MSNs-7 with enhanced fluorescence intensity (2.3-fold) after the removal of CTAB but also bring about high accessible surface area (606.6 m(2)/g) and larger pore size (3.2 nm) and pore volume (0.634 cm(3)/g) for effective loading and sustained release of the hydrophobic anticancer drug camptothecin. C-TPE-C-6-C-TPE enriches the family of gemini surfactants and provides important insights into the convenient fabrication of advanced fluorescent mesoporous materials.

• 出版日期2018-11-5
• 单位武汉大学; 中国地质大学（北京）