A facile preparation of N-methylpentan-1-amine: A key intermediate for ibandronate sodium

作者：Reddy V V R M Krishna; Chintamani U S; Udaykiran D; Madhusudhan C^*; Mukkanti K

来源：Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry , 2010, 49(9): 1257-1260.

• N-Methylpentan-1-amine
• ibandronate sodium
• anti-osteoclast agent
• cost effective

A facile preparation of N-methylpentan-1-amine, which is a key intermediate for the synthesis ibandronate sodium, an anti-osteoclast agent is described. This route is cost effective over the previous methods. Part or this work could be an easy access for the preparation of various N,N-alkyl of aryl amine derivatives.

• 出版日期2010-9