摘要
A simple procedure for the synthesis and characterization of new 3-alkoxy-3-(1H-tetrazol-5-yl)propionic acids and 2-(1H-tetrazol-5-yl)tetrahydrofuran- and -(1H-tetrazol-5-yl)-2H-pyran-3-carboxylic acids from the [2+3] cycloaddition reactions between the nitrile group of -cyanocarboxylic acids with sodium azide in the presence of zinc chloride is described. The tetrazolic acids were isolated in moderate to good yields and are structurally analogous to succinic acid.
- 出版日期2013-7