Health-related quality of life is worse in individuals with hypertension under drug treatment: results of population-based study

作者：Trevisol D J; Moreira L B; Fuchs F D^*; Fuchs S C

来源：Journal of Human Hypertension, 2012, 26(6): 374-380.

DOI：10.1038/jhh.2011.48

• blood pressure
• quality of life
• Short-Form Health Survey
• SF-12

Patients with hypertension usually report lower health-related quality of life (HRQoL), but it is unclear whether this is secondary to high blood pressure (BP) per se, drug treatment or awareness of disease. In a cross-sectional study using a multistage population-based sample, participants were interviewed and examined at home. Hypertension was defined by BP >= 140/90 mm Hg or use of BP-lowering drugs. HRQoL was assessed through the Short-Form Health Survey (SF-12) and presented as the physical component summary (PCS), mental component summary (MCS) and the SF-12 eight-domain scale. In total, 1858 individuals were evaluated, being 60.1% women, aged 52.5 +/- 4.1 years old, and 39.9% men, aged 47.2 +/- 9.1 years old. Prevalence of hypertension was 34.2% (95% CI 31.5-36.9). The PCS scores for hypertensive and normotensive participants were 49.4 (CI 48.6-50.2) and 51.06 (CI 50.4-51.7) (P = 0.01), respectively, and the MCS scores were 49.1 (CI 47.9-50.3) and 50.5 (CI 49.6-51.2) (P = 0.06), respectively. Participants with hypertension and not using BP drugs had higher HRQoL scores (PCS 49.6; MCS 51.9) than those using BP drugs either with uncontrolled (PCS 45.3; MCS 49.4) or controlled BP (PCS 46.2; MCS 47.7; P<0.05). We concluded that individuals with hypertension have worse quality of life, particularly when their BP is controlled by drugs. This perception may lead to lower rates of adherence to treatment. Journal of Human Hypertension (2012) 26, 374-380; doi:10.1038/jhh.2011.48; published online 19 May 2011

• 出版日期2012-6