A European survey of perendoscopic treatment of biliary complications in patients with alveolar echinococcosis

作者：Ambregna Sylvain; Koch Stephane; Sulz Michael C; Gruener Beate; Oeztuerk Suemeyra; Chevaux Jean Baptiste; Sulima Malgorzata; de Gottardi Andrea; Napoleon Bertrand; Abergel Armand; Bichard Philippe; Boytchev Isabelle; Deprez Pierre; Dumortier Jerome; Frossard Jean Louis; Kull Eric; Meny Bernard; Moradpour Darius; Prat Frederic; Vanbiervliet Geoffroy; Thevenot Thierry; Vuitton Dominique Angele; Bresson Hadni Solange; Vuitton Lucine^*

来源：Expert Review of Anti-Infective Therapy, 2017, 15(1): 79-88.

DOI：10.1080/14787210.2017.1252260

• Endoscopic retrograde cholangio-pancreatography (ERCP)
• alveolar echinococcosis (AE)
• Echinococcus multilocularis
• biliary stricture
• biliary stent
• cholangitis

Background: Biliary complications represent a turning point in the course of Alveolar Echinococcosis (AE). We conducted a European survey to collect data on the current usage and results of perendoscopic interventions (PEIs) for their treatment.Methods: Patient's characteristics and follow-up until January 31st, 2015 were recorded using an online questionnaire.Results: From 18 centers 129 PEIs were analyzed in 38 patients; 139 plastic stents were inserted during 85 PEIs; median time between stent placements was significantly longer when 3 stents or more were placed. Initial symptoms disappeared in 95% and long-term bile duct patency was obtained in 73% of cases. Cholangitis was a more frequent complication of the PEIs (10%) than in other indications; intensive lavage of the bile ducts may prevent this complication.Conclusion: European centers use perendoscopic biliary drainage as an efficient and safe alternative to surgery to treat AE biliary complications. Insertion of multiple plastic stents delays stent occlusion and leads to effective and prolonged bile duct patency.

• 出版日期2017-1