Feasibility of Tomotherapy for Graves' Ophthalmopathy Dosimetry Comparison with Conventional Radiotherapy

作者：Nguyen Nam P^*; Krafft Shane P; Vos Paul; Vinh Hung Vincent; Ceizyk Misty; Jang Siyoung; Desai Anand; Abraham Dave; Ewell Lars; Watchman Christopher; Hamilton Russ; Jo Beng Hoey; Karlsson Ulf; Smith Raymond Lexie

来源：Strahlentherapie und Onkologie, 2011, 187(9): 568-574.

DOI：10.1007/s00066-011-2220-z

• Graves exophthalmos
• Tomotherapy
• Target coverage

Purpose: To compare the dosimetry of tomotherapy and the conventional half-beam technique (HBT) or non-split beam technique (NSBT) for target coverage and radiation dose to the lacrimal glands and lens.
Patients and Methods:A retrospective review of 7 patients with Graves' ophthalmopathy who had radiotherapy because of disease progression on high steroid dose is reported: 3 patients were treated with tomotherapy and 4 patients with HBT.
Results:Compared to HBT, tomotherapy may provide better target coverage and significant reduction of radiation dose to the lacrimal glands and a higher dose to the lens. The NSBT improved target coverage but resulted in significantly higher doses to the lens and lacrimal glands.
Conclusion:Tomotherapy may provide better coverage of the target volume and may be more effective in reducing severe exophthalmos compared to the conventional radiotherapy technique.

• 出版日期2011-9