Differentiation of low- and high-grade clear cell renal cell carcinoma: Tumor size versus CT perfusion parameters

作者：Chen, Chao; Kang, Qinqin; Xu, Bing; Guo, Hairuo; Wei, Qiang; Wang, Tiegong; Ye, Hui; Wu, Xinhuai^*

来源：Clinical Imaging, 2017, 46: 14-19.

DOI：10.1016/j.clinimag.2017.06.010

• Computed tomography
• Perfusion imaging
• Clear cell renal cell carcinoma
• Size
• Fuhrman grade

Purpose: To compare the utility of tumor size and CT perfusion parameters for differentiation of low- and high-grade clear cell renal cell carcinoma (RCC). Materials and methods: Tumor size, Equivalent blood volume (Equiv BV), permeability surface-area product (PS), blood flow (BF), and Fuhrman pathological grading of clear cell RCC were retrospectively analyzed. Results: High-grade clear cell RCC had significantly higher tumor size and lower PS than low grade. Tumor size positively correlated with Fuhrman grade, but PS negatively did. Conclusions: Tumor size and PS were significantly independent indexes for differentiating high-grade from low-grade clear cell RCC.

• 出版日期2017-12
• 单位湖南省肿瘤医院; 中国人民解放军第二军医大学