Advances in dissecting mosquito innate immune responses to arbovirus infection

作者:Fragkoudis Rennos; Attarzadeh Yazdi Ghassem; Nash Anthony A; Fazakerley John K; Kohl Alain*
来源:Journal of General Virology, 2009, 90(9): 2061-2072.
DOI:10.1099/vir.0.013201-0

摘要

Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signal ling pathways, and cell death/apoptosis.

  • 出版日期2009-9