科研之友
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摘要
A drastic enhancement in catalytic activity was observed by the introduction of steric hindrance ortho to the iodine atom of catalysts used for the alpha-tosyloxylation of ketones. Through structural analysis and density functional theory calculations, we explain the origin of this acceleration effect and show its significance through a first example of a chiral catalyst exploiting this feature.
- 出版日期2012-2
