A novel and efficient method combining SFE and liquid-liquid extraction for separation of coumarins from Angelica dahurica

作者：Wang Long Hu; Mei Yan Hong; Wang Feng; Liu Xue Song; Chen Yong^*

来源：Separation and Purification Technology, 2011, 77(3): 397-401.

DOI：10.1016/j.seppur.2010.12.020

• Angelica dahurica
• Coumarins
• Supercritical fluid extraction
• SFE
• LLE

Nowadays supercritical fluid extraction (SFE) as an alternative is popular in food and pharmaceutical industries but its large scale application is often restricted economically by the confliction between recovery efficiency and selectivity. In this article, a simple but novel and efficient combined method was investigated for separating coumarins from Angelica dahurica. The experimental results showed that combining SFE and liquid-liquid extraction could improve both extraction selectivity and separation efficiency, enriching easily coumarins from 0.144% in the herb to as much as 41.68% in the concentrate.

• 单位
  浙江大学