An efficient method for synthesis of 3-arylbenzo[f]quinoline-1,2-dicarboxylates catalyzed by SnCl2

作者:Yan Qing; Zang Hongjun*; Feng Jiaxuan; Li Mingguang; Yang Danni; Lu Hai; Cheng Bowen
来源:Research on Chemical Intermediates, 2015, 41(10): 6967-6974.
DOI:10.1007/s11164-014-1791-6

摘要

A wide variety of 3-arylbenzo[f]quinoline-1,2-dicarboxylates and their dehydro derivatives have been synthesized by one-pot, three-component reaction of an aromatic aldehyde, naphthalene-2-amine, and dimethyl but-2-ynedioate in the presence of SnCl2 under reflux in acetonitrile. This procedure has several advantages, for example high yield, short reaction time, easy work-up, little pollution, and low price of the catalyst.

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