Diarylethene based fluorescent switchable probes for the detection of amyloid-β pathology in Alzheimer's disease

作者:Lv, Guanglei; Cui, Baiping; Lan, Haichuang; Wen, Ying; Sun, Anyang*; Yi, Tao
来源:Chemical communications, 2015, 51(1): 125-128.
DOI:10.1039/c4cc07656g

摘要

Two fluorescent switchable diarylethene derivatives which exhibit high affinity for amyloid-beta aggregates with the increase of fluorescence intensity were reported. Moreover, the probes show excellent photochromic and anti-photobleaching properties both in vitro and in vivo.