Analyzing and identifying risk factors for acute pancreatitis with different etiologies in pregnancy

作者：Jin, Jin; Yu, Yan-hong; Zhong, Mei; Zhang, Guo-wei^*

来源：Journal of Maternal-Fetal and Neonatal Medicine, 2015, 28(3): 267-271.

DOI：10.3109/14767058.2014.913132

• Biliary acute pancreatitis
• hyperglyceridemic-induced pancreatitis
• pregnancy
• risk

Objective: To identify the risk factors of acute pancreatitis (AP) associated with different etiologies, in pregnancy (APP).
Methods: Forty-seven eligible patients were divided into two groups: biliary acute pancreatitis in pregnancy (BAPP, n = 31) and hypertriglyceridemic-induced pancreatitis in pregnancy (HAPP, n = 16). Multivariate analysis was utilized in identifying independent risk factors of BAPP and HAPP.
Results: The independent risk factors of BAPP included gallbladder stones (OR, 3.924; p = 0.007) and high-fat diet in pregnancy (OR, 4.878; p = 0.001). Hypertriglyceridemia (OR, 3.667; p = 0.035) was the only independent risk factor for HAPP. Based on the severity of AP, no significant differences in adverse outcomes were found between BAPP and HAPP.
Conclusions: High-fat diet should be prohibited for gravida with biliary diseases. Compared to biliary tract stones, the study observed that gallstones were more likely to cause AP for pregnant women. Hypertriglyceridemic pregnant women were found to be more susceptible to AP.

• 出版日期2015-2
• 单位南方医科大学