A sequential synthesis of substituted furans from aryl alkynes and ketones involving a cerium(IV) ammonium nitrate (CAN)-mediated oxidative cyclization

作者：Undeela Sridhar; Ramchandra Joshi P; Menon Rajeev S^*

来源：Tetrahedron Letters, 2014, 55(41): 5667-5670.

DOI：10.1016/j.tetlet.2014.08.039

• Furans
• Cerium(IV) ammonium nitrate
• Oxidative cyclization
• Alkynes
• Ketones

A convenient, two-step synthesis of substituted furans from readily available aryl alkynes and ketones is reported. The furan-forming oxidative cyclization is mediated by the combination of cerium(IV) ammonium nitrate and potassium bromide and can be carried out in an open flask.

• 出版日期2014-10-8