Antitumor and Antioxidant Activities of Extracts from Cyrtomium fortumei (J.) Smith

作者:Yang Sheng Jie; Liang Na; Hu De Yu; Xiang Hong Mei; Xue Wei; Yang Song
来源:Asian Journal of Chemistry, 2013, 25(14): 7761-7764.
DOI:10.14233/ajchem.2013.14596

摘要

The in vitro antitumor activities of crude petroleum ether, ethyl acetate and n-BuOH extracts of Cyrtomium fortumei (J.) Smith were studied on the A375, Bcap-37, BGC-823 and PC3 cell lines. The antioxidant activities of these crude extracts were also tested by DPPH (2,2-diphenlyl-1-picrylhydrazyl) radical scavenging assay. The results relvealed that ethyl acetate and n-BuOH extracts showed significant antitumor activities and exhibited high DPPH free radical scavenging effects. In addition, Fr.5 isolated from ethyl acetate extract had good antitumor activities and the inhibitory ratios of Fr.5 at 100 mu g/mL were 82.4, 81.2, 75.1 and 80.9 % against the four cell lines respectively.