Mitochondria on the move: BMSCs fuel AML energy

作者：Lapalombella Rosa^*

来源：Blood, 2017, 130(14): 1603-1604.

DOI：10.1182/blood-2017-08-798504

<jats:p>In this issue of Blood, Marlein et al1 identify a tumor-specific NOX2-dependent transfer of mitochondria from bone marrow stromal cells (BMSCs) to acute myeloid leukemia (AML) cells via AML-derived tunneling nanotubes (see figure), supporting inhibition of NOX2 as a novel therapeutic strategy in AML.</jats:p>

• 出版日期2017-10-5