A Case of IgG4-Related Disease with Bronchial Asthma and Chronic Rhinosinusitis in Korea

作者：Lee Young Soo; Cho Hyo Jeong; Yoo Hye Soo; Shin Yoo Sub; Park Hae Sim^*

来源：Journal of Korean Medical Science, 2014, 29(4): 599-603.

DOI：10.3346/jkms.2014.29.4.599

• IgG4-Related Disease
• Asthma
• Bronchitis, Chronic

IgG4-related disease (IgG4-RD) is characterized by a systemic involvement of tumor-like lesions with IgG4-positive plasmacytes. We experienced a case of IgG4-RD developed in a patient with bronchial asthma (BA) and chronic rhinosinusitis (CRS). A 55-yr-old female patient with BA and CRS complained of both eyes and neck swelling as well as a recurrent upper respiratory infection in recent 1 yr. The serum levels of IgG4, creatinine, and pancreatic enzymes were elevated. A biopsy of the submandibular gland showed an abundant infiltration of IgG4-positive plasmacytes. Her symptoms remarkably improved after the treatment of a systemic steroid that has been maintained without recurrence. We report a rare case of IgG4-RD developed in a patient with BA and CRS.

• 出版日期2014-4