Phenolic content, antioxidant and enzyme inhibitory capacity of two Trametes species

作者：Zengin Gokhan; Karanfil Abdullah; Uren Mehmet Cemil; Kocak Mehmet Sefa; Sarikurkcu Cengiz; Gungor Halil; Picot Carene Marie Nancy; Mahomoodally Mohamad Fawzi

来源：RSC Advances, 2016, 6(77): 73351-73357.

DOI：10.1039/c6ra09991b

The phenolic composition, antioxidant and enzyme inhibitory activities of methanolic and water extracts of Trametes gibbosa (TG) and Trametes hirsuta (TH) were characterised for the first time. Reversed-phase high-performance liquid chromatography (RP-HPLC) analysis revealed that TG and TH methanolic extracts contained (+)-catechin, chlorogenic acid and caffeic acid. Methanolic extracts of TG and TH showed significantly (p < 0.05) high inhibition rates on acetyl (1.87 and 1.60 mg galantamine equivalents (GALAEs) per g extract respectively) and butyryl cholinesterase (1.71 and 1.90 mg GALAEs per g extract respectively). Low and insignificant inhibition was observed against alpha-amylase. alpha-Glucosidase inhibitory activity of TG (0.93 mmol acarbose equivalents (ACEs) per g extract) and TH (1.18 mmol ACEs per g extract) methanolic extracts were significantly (p < 0.05) high. Methanolic extract of TG (16.85 +/- 0.29 TEs per g extract) and TH (13.86 +/- 0.03 mg TEs per g extract) showed the most effective cupric reducing power. This study tends to support the potential use of these mushrooms species for designing new functional food formulations.

• 出版日期2016