A voltage-gated sodium channel mediates positive selection of T cells

作者：Malissen Bernard^*

来源：Nature Immunology, 2012, 13(9): 810-812.

DOI：10.1038/ni.2400

The activation of T cells requires the entry of calcium ions through the plasma membrane. A study now identifies a voltage-gated sodium channel as being essential for the sustained entry of calcium needed for the developmental process of positive selection.

• 出版日期2012-9