A Systematic Review of Current Understanding and Management of Mastalgia

作者：Kataria Kamal; Dhar Anita; Srivastava Anurag^*; Kumar Sandeep; Goyal Amit

来源：Indian Journal of Surgery, 2014, 76(3): 217-222.

DOI：10.1007/s12262-013-0813-8

• Mastalgia
• Cyclical mastalgia
• Noncyclical mastalgia
• Centchroman
• Danazol
• Diclofenac gel

Breast pain or mastalgia is the common symptom in the breast. The two most common concerns of patients presenting with mastalgia are: the fear that breast pain is a symptom of breast cancer and the presence of severe pain that affects a woman's quality of life. Breast pain requires thorough assessment and should be investigated in the same manner as any other breast symptom. We conducted a systematic review of treatment for breast pain. We searched various reviews, randomized controlled trial, and observational studies over Pubmed and Medline via internet. Searches were carried out on MEDLINE (1950-present), EMBASE (1980-present), and CINAHL (1981-present) using the NHS Evidence Healthcare Databases Advanced Search interface. A further search was also carried out on Cochrane Database of Systematic Reviews (issue 12 of 12, Dec 2011) and Central Register of Controlled Trials (issue 4 of 4, Oct 2011). If no abnormality is found in the breast on assessment, then a combination of reassurance, breast support brassiere, and topical NSAID gel massage are usually effective. Antiestrogen (centchroman/tamoxifen) therapy for 3 to 6 months is the second-line treatment of choice. Danazol may be used in resistant cases. Gamma-linolenic acid or evening primrose oil though commonly prescribed is not effective.

• 出版日期2014-6
• 单位河北医科大学