科研之友
微信
新浪微博
Facebook
分享链接
摘要
The majority of laboratory animals is a prey in nature, therefore they can be used in the fields of many pshychological researches, such as modeling different human anxiety syndromes. Previously the rat used to be the primary model, but parellel to the development of molecular biology, sensitive transgenic mouse models appeared. To be able to effectively use these animals, the authors overview the natural behaviour of mice and their reaction in answering various situations. There are great differences amongst the phenotypes of the individual strains and lines, including behaviour and temperament, for example the CD1 mice are calm, the BALB/c ones rather irritate (Figure 1-3). In addition, during the experimentation a kind of environment should be assured mice to gratify their natural action catalogue, prevent influencing the results of the tests. The environmental enrichment influences animals' ethology, physiology and brain functions. The acoustic enrichment of the environment, namely the use of musical sound stimuli, became more and more preferred. A continuous background music may appease animals and decrease the stress of the constant, inevitable and abrupt noises. Moreover, it might have an effect on human, working with the animals and by this way may also influence the latter. The assumption is logical that the use of music might help to improve animal welfare and assure the standardisation and repeatability of experiments, as well as the reliability of the results. To achieve this, sufficient information is required about the musical preference of the most important experimental animal, the mouse and its strains: which type of music, in which hearing ranges and frequencies, applied in which circumstances are different or even harmful.
- 出版日期2016-11
