Depression is correlated with the psychological and physical aspects of sexual dysfunction in men

作者：Pastuszak A W; Badhiwala N; Lipshultz L I; Khera M^*

来源：International Journal of Impotence Research, 2013, 25(5): 194-199.

DOI：10.1038/ijir.2013.4

• ADAM
• depression
• IIEF
• male sexual function
• PHQ-9

Few studies have objectively examined the relationship between depression and various stages of sexual function. Here we associate depression and sexual function using validated questionnaires. A retrospective review of 186 men was performed; demographics and serum hormone levels were obtained. Responses to questionnaires evaluating depressive symptoms (Patient Health Questionnaire (PHQ-9)), sexual International Index of Erectile IIEF)) and hypogonadal symptoms (quantitative Androgen Decline in the Aging Male (qADAM)) completed by each patient were correlated using Spearman%26apos;s rank correlation. Mean +/- s.d. subject age: 52.6 +/- 12.7 years; mean serum hormone levels: TT 429.8 +/- 239.2 ng dl(-1), free testosterone 9.72 +/- 7.5 pg ml(-1) and estradiol 34.4 +/- 22.8 pg ml(-1). Negative correlations were observed between total PHQ-9 score and the sexual desire (rho = -0.210, P = 0.006), intercourse satisfaction (rho = -0.293, P%26lt;0.0001) and overall satisfaction (rho = -0.413, P%26lt;0.0001) domains of the IIEF and individual IIEF questions pertaining to erectile function. Men with a PHQ-9 score %26gt;= 10 (mild depression or worse), had lower sexual desire and sex life satisfaction. A negative correlation between PHQ-9 score and qADAM score (rho = -0.634, P%26lt;0.0001) was observed and men with higher PHQ-9 score had lower qADAM scores. Depressive symptoms in men correlate with both psychological as well as physical aspects of sexual function.

• 出版日期2013-10