Body composition and bone mineral density in users of the etonogestrel-releasing contraceptive implant

作者：Modesto Waleska^*; DalAva Natalia; Monteiro Ilza; Bahamondes Luis

来源：Archives of Gynecology and Obstetrics, 2015, 292(6): 1387-1391.

DOI：10.1007/s00404-015-3784-0

• Etonogestrel-releasing implant
• Bone mineral density
• Body composition

There is scarce information about bone mineral density (BMD) and body composition (BC) among users of the etonogestrel (ENG)-releasing implant.
To evaluate BC and BMD in ENG-releasing implant users as compared to copper intrauterine device (Cu-IUD)-users.
A prospective study was conducted on 75 users of both contraceptive methods. BMD was evaluated at femoral neck (FN) and lumbar spine (LS) (L1-L4) and BC at baseline and at 12 months after insertion.
The mean (+/- SD) age was 30.4 +/- A 6.8 and 29.8 +/- A 8.4 years and body mass index (kg/m(2)) was 24.9 +/- A 4.1 and 24.6 +/- A 3.5 in ENG-releasing implant- and Cu-IUD-users, respectively. ENG-releasing implant users did not show significant differences on BMD at the LS and FN at 12 months of use. Furthermore, ENG-implant users had an increase in body weight at 12 months (p < 0.001) and an increase of 2 % in the percentage of body fat, when compared with Cu-IUD users. There was a significant increase in lean mass in ENG-implant users at 12 months (p = 0.020).
No significant changes of BMD were seen after the first year of use among the ENG-releasing implant-users, albeit an increase of weight and fat mass was seen when compared to Cu-IUD users.

• 出版日期2015-12