摘要

Ethyl 7-aryl-2-benzylthiopyrazolo [1, 5-a] pyrimidine-3-carboxylates ( 3a-3f) were conveniently synthesized through the reactions of enaminones with 5-amino-3-benzylthio-4-ethoxycarbonyl-1H-pyrazole in good yields and high regioselectivity. The structures of the new compounds were fully characterized by spectroscopic measurments, elemental analysis and X-ray diffraction analysis. A plausible reaction mechanism for the formation of the title compounds was also presented.