科研之友
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摘要
The temporospatial regulation of axon outgrowth is useful for guiding de novo connectivity or reconnectivity of neurons in neurological injury or disease. Here we report the successful construction of a biocompatible guidance device, in which a linear propagation of IGF-1 gradient sequentially directs axon outgrowth. We observe the extensive in vitro axonal extension over 5 mm with a desired growth rate of similar to 1 mm/day.
- 出版日期2014-8-6
