A Cryptic Subgroup of Anopheles gambiae Is Highly Susceptible to Human Malaria Parasites

作者：Riehle Michelle M; Guelbeogo Wamdaogo M; Gneme Awa; Eiglmeier Karin; Holm Inge; Bischoff Emmanuel; Garnier Thierry; Snyder Gregory M; Li Xuanzhong; Markianos Kyriacos; Sagnon N'Fale; Vernick Kenneth D^*

来源：Science, 2011, 331(6017): 596-598.

DOI：10.1126/science.1196759

Population subgroups of the African malaria vector Anopheles gambiae have not been comprehensively characterized owing to the lack of unbiased sampling methods. In the arid savanna zone of West Africa, where potential oviposition sites are scarce, widespread collection from larval pools in the peridomestic human habitat yielded a comprehensive genetic survey of local A. gambiae population subgroups, independent of adult resting behavior and ecological preference. A previously unknown subgroup of exophilic A. gambiae is sympatric with the known endophilic A. gambiae in this region. The exophilic subgroup is abundant, lacks differentiation into M and S molecular forms, and is highly susceptible to infection with wild Plasmodium falciparum. These findings might have implications for the epidemiology of malaria transmission and control.

• 出版日期2011-2-4