A Case of Transient Central Diabetes Insipidus after Aorto-Coronary Bypass Operation

作者：Yu Chung Hoon; Cho Jang Hee; Jung Hee Yeon; Lim Jeong Hoon; Jin Mi Kyung; Kwon Owen; Hong Kyung Deuk; Choi Ji Young; Yoon Se Hee; Kim Chan Duck; Kim Yong Lim; Kim Gun Jik; Park Sun Hee^*

来源：Journal of Korean Medical Science, 2012, 27(9): 1109-1113.

DOI：10.3346/jkms.2012.27.9.1109

• Polyuria
• Central Diabetes Insipidus
• Aorto-Coronary Bypass

Diabetes insipidus (DI) is characterized by excessive urination and thirst. This disease results from inadequate output of antidiuretic hormone (ADH) from the pituitary gland or the absence of the normal response to ADH in the kidney. We present a case of transient central DI in a patient who underwent a cardiopulmonary bypass (CPB) for coronary artery bypass grafting (CABG). A 44-yr-old male underwent a CABG operation. An hour after the operation, the patient developed polyuria and was diagnosed with central DI. The patient responded to desmopressin and completely recovered five days after surgery. It is probable that transient cerebral ischemia resulted in the dysfunction of osmotic receptors in the hypothalamus or hypothalamus-pituitary axis during CPB. It is also possible that cardiac standstill altered the left atrial non-osmotic receptor function and suppressed ADH release. Therefore, we suggest that central DI is a possible cause of polyuria after CPB.

• 出版日期2012-9