Secondary Hyperparathyroidism: Pathophysiology and Treatment

作者:Saliba Wissam*; El Haddad Boutros
来源:Journal of the American Board of Family Medicine, 2009, 22(5): 574-581.
DOI:10.3122/jabfm.2009.05.090026

摘要

Secondary hyperparathyroidism is a frequently encountered problem in the management of patients with chronic kidney disease (CKD). Its pathophysiology is mainly due to hyperphosphatemia and vitamin D deficiency and resistance. This condition has a high impact on the mortality and morbidity of dialysis patients. Early diagnosis of secondary hyperparathyroidism is crucial in the management of patients with CKD. The treatment remains a challenge for patients and their clinicians. It should include a combination of dietary phosphorus restriction, phosphate binders, vitamin D analogues, and calcimimetics. (J Am Board Fam Med 2009; 22: 574-581.)

  • 出版日期2009-10