摘要
A novel structurally simple and easily prepared pH probe based on a twisted intramolecular charge transfer signalling mechanism, namely Napa-pp, has been designed and synthesized. In aqueous buffer solution, it has a valuable pK(a) of 5.32 that matches the typical pH range of acidic organelles, hence it is applicable for visualizing lysosomes in living cells.
- 出版日期2014
- 单位波谱与原子分子物理国家重点实验室; 中国科学院; 四川大学; 中国科学院武汉物理与数学研究所