Microbial synthesis of dihydrochalcones using Rhodococcus and Gordonia species

作者：Stompor Monika; Potaniec Bartlomiej; Szumny Antoni; Zielinski Pawel; Zolnierczyk Anna Katarzyna; Aniol Miroslaw^*

来源：Journal of Molecular Catalysis B: Enzymatic , 2013, 97: 283-288.

DOI：10.1016/j.molcatb.2013.09.009

• Biotransformation
• Flavonoids
• Gordonia sp.
• Rhodococcus sp.
• Hydrogenation

Chalcones are important compounds in food and cosmetics industry, and in food chemistry research. We have developed a method of synthesis of dihydrochalcones from flavanone and alpha,beta-unsaturated chalcones by microbial hydrogenation. It has been found that bacterial strains of Rhodococcus sp. and Gordonia sp. can be successfully used in the key step of dihydrochalcones synthesis. This kind of activity has not been previously examined.
Twelve microorganisms were initially screened for their ability to catalyze biotransformation reactions of selected flavonoid compounds. Of these, Rhodococcus sp. and Gordonia sp. transformed flavanone and chalcones to hydrogenation products in good isolated yield of 13-94%.

• 出版日期2013-12-15