A propensity-matched comparison of perioperative complications and of chronic kidney disease between robot-assisted laparoscopic partial nephrectomy and radiofrequency ablative therapy

作者：Kim Sung Han; Lee Eun Sik; Kim Hyeon Hoe; Kwak Cheol; Ku Ja Hyeon; Lee Sang Eun; Hong Sung Kyu; Jeong Chang Wook; Kim Seung Hyup; Cho Jeong Yeon; Hwang Sung Il; Lee Hak Jong; Byun Seok Soo^*

来源：Asian Journal of Surgery, 2015, 38(3): 126-133.

DOI：10.1016/j.asjsur.2014.09.005

• ablation techniques
• renal cell carcinoma
• laparoscopy
• nephrectomy
• pulsed radiofrequency ablation treatment

Objective: The study presents a matched-pair analysis of robot-assisted laparoscopic partial nephrectomy (RALPN) versus radiofrequency ablation (RFA) to compare the perioperative incidence of complications and chronic kidney disease (CKD).
Methods: All 46 RFA and 206 RALPH cases from June 2005 to December 2011 were retrospectively reviewed from the medical records and were matched 1:1 based on propensity scores by sex, tumor size, tumor laterality of kidney, tumor location within the kidney, and clinical T stage. Hilar vessel clamping was performed in all RALPH patients. The estimated glomerular filtration rate was used to define the CKD of < 60 mL/minute/1.73 m(2) by the Modification of Diet in Renal Disease equation. All patients with baseline CKD or solitary kidney were excluded prior to the matching analysis. The complication was noted with modified Clavien grades >= 3. Statistical analysis was performed to compare the perioperative incidence of complications and CKD.
Results: A total of 27 matched pairs of RFA and RALPH patients were enrolled for analyzing CKD and perioperative complications. The better general conditions, higher estimated blood loss and transfusion rates, and longer operative time and hospital stay were observed significantly in RALPN patients (p < 0.05). Matched analysis demonstrated that the incidences of both perioperative complications (p = 0.434) and of CKD (p = 0.500) were not significantly different. No complication higher than Grade 4 was detected in either group.
Conclusion: Despite the intraoperative renal ischemia and invasiveness of the procedure associated with RALPN, the incidence of perioperative complication and of CKD developing rates were statistically similar.

• 出版日期2015-7