A fluorescent probe for the selective detection of creatinine in aqueous buffer applicable to human blood serum

作者:Pal Siddhartha; Lohar Somenath; Mukherjee Manjira; Chattopadhyay Pabitra*; Dhara Koushik*
来源:Chemical communications, 2016, 52(94): 13706-13709.
DOI:10.1039/c6cc07291g

摘要

A naphthalimide-based fluorescence light-up probe, FCP-Pd, has been designed and synthesized for selective detection and quantitation of creatinine in PBS buffer of pH 7.2 at 37 degrees C with a 'turn-on' response over a variety of interfering metal ions and/or anions and several biologically significant species. This probe is highly effective in estimating creatinine in human blood serum, which confirms the reliability and accuracy of this new system to be applied in clinical and toxicological analysis.

  • 出版日期2016