Application of Proline-Functionalised 1,2-Diphenylethane-1,2-diamine (DPEN) in Asymmetric Transfer Hydrogenation of Ketones

作者：Manville Charles V; Docherty Gordon; Padda Ranbir; Wills Martin^*

来源：European Journal of Organic Chemistry, 2011, (34): 6893-6901.

DOI：10.1002/ejoc.201101164

• Asymmetric catalysis
• Hydrogenation
• Ruthenium
• Iridium
• Peptides

A series of enantiomerically pure ligands containing a combination of proline and DPEN groups have been prepared and employed in the asymmetric transfer hydrogenation of ketones. In the case of cyclic ketones, alcohols with ee values of up to 98?% were obtained.

• 出版日期2011-12