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摘要
A facile synthesis for novel loperamide analogs as potential mu opioid receptors is described. The synthetic procedure for compound 5, which contains two 4-phenyl piperidine scaffolds, was optimized, and this compound was synthesized in excellent yield. We also describe a mild and highly efficient protocol for the synthesis of compounds 6 and 7.
- 出版日期2012-12
- 单位南京理工大学
