Multivesicular release and saturation of glutamatergic signalling at retinal ribbon synapses

作者：Singer Joshua H^*

来源：The Journal of Physiology, 2007, 580(1): 23-29.

DOI：10.1113/physiol.2006.125302

Pronounced multivesicular release (MVR) occurs at the ribbon synapses of sensory neurones that signal via graded potential changes. As MVR increases the likelihood of postsynaptic receptor saturation, it is of interest to consider how sensory synapses overcome this problem and use MVR to encode signals of widely varying intensities. Here, I discuss three postsynaptic mechanisms that permit three different retinal synapses to utilize MVR.

• 出版日期2007-4-1
• 单位西北大学