A new generation electrochemical sensor based on Graphene nanosheets/Gold nanoparticles/Nafion nanocomposite for determination of Silodosin

作者：Er Engin; Celikkan Huseyin; Erk Nevin; Aksu M Levent^*

来源：Electrochimica Acta, 2015, 157: 252-257.

DOI：10.1016/j.electacta.2015.01.020

• Electrochemical sensor
• Graphene
• Chemical modified electrode
• Gold nanoparticle
• Silodosin

It is the first time that a rapid, facile, highly sensitive and selective electrochemical sensor based on graphene nanosheets/gold nanoparticles/nafion nanocomposite modified electrode (GRP/AuNPs/NFN) was developed for the electro-oxidation and quantification of silodosin (SLD). The chemical formation of GRP/AuNPs nanocomposite was verified by x-ray diffraction (XRD), fourier transform infrared spectroscopy (FT-IR) and transmission electron spectroscopy (TEM). The electrochemical oxidation of SLD has been investigated at GRP/AuNPs/NFN by the use of adsorptive stripping differential pulse voltammetry (AdSDPV). The developed electrode exhibited excellent electrochemical activity towards the electrochemical oxidation of SLD. Under optimal conditions, GRP/AuNPs/NFN demonstrated a wide linearity ranging from 10-330 nM with a detection limit of 3.8 nM (S/N = 3). Therefore, the electrode developed can conveniently be used for the electroanalytical determination of SLD in pharmaceutical or biological samples.

• 出版日期2015-3-1