A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals (Retracted article. See vol. 2, 839, 2012)

作者：Moriguchi Hisashi^*; Zhang Yue; Mihara Makoto; Sato Chifumi

来源：Scientific Reports, 2012, 2: 280.

DOI：10.1038/srep00280

Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic method may be applicable to various human solid tumor cells that express aldo-keto reductase family 1 member B10 (AKR1B10) and retinoid X receptors (RXRs).

• 出版日期2012-2-21