Assessment and Intervention Thresholds to Detect Cases at Risk of Osteoporosis and Fragility Fractures with FRAX (R) in a Mexican Population for the First Level of Healthcare

作者：Clark Patricia^*; Ramirez Perez Esperanza; Reyes Lopez Alfonso

来源：Gaceta Medica de Mexico, 2016, 152: 22-31.

• Osteoporosis
• Thresholds
• Evaluation
• Risk
• FRAX (R)

Objective: To estimate the evaluation and intervention thresholds using FRAX (R) in Mexican population. Methods: Probabilities for a mayor fracture using the Mexican FRAX (R) version to estimate the evaluation and intervention thresholds using clinical scenarios were obtained in both sexes 40 years and over. Projections for 2020 were done to estimate the number of patients at the intervention level taking the osteoporosis prevalence in Mexicans aged 50 years and over. Results: The cutoffs for the intervention thresholds were 2.6%-20.0%. Individuals with thresholds above these probabilities are amenable for intervention. The assessment thresholds range from 1.2-3.2% to 12.5-24.4% for 40 to 90 years. According to projections of our population,approximately three million people are susceptible to intervention by 2020. Conclusion: The use of FRAX (R) thresholds of intervention and evaluation developed in this study will be useful in the primary care level for case detection at high risk of fragility fracture.

• 出版日期2016-10