A postmeningitic cochlear implant patient who was postoperatively diagnosed as having X-linked agammaglobulinemia

作者：Minoda Ryosei^*; Takahashi Haruo; Miyamaru Satoru; Masuda Masako; Miwa Toru; Sanuki Tetsuji; Hirai Toshinori; Yumoto Eiji

来源：Auris Nasus Larynx, 2012, 39(6): 638-640.

DOI：10.1016/j.anl.2011.12.005

• X-linked agammaglobulinemia
• Primary immunodeficiency
• Cochlear implant

X-linked agammaglobulinemia (XLA) is caused by a mutation in the Bruton tyrosine kinase, leading to an arrest in B cell development. Consequently, patients with XLA show significant decreases in gammaglobulin. Here, we describe a child with postmeningitic deafness and XLA who underwent a cochlear implantation. His psychomotor development had been normal and his congenital immunodeficiency was noticed only postoperatively. Immunoglobulin replacement treatment was started, but he still suffered repeated infections. Eventually, his cochlear implant was removed. A preoperative check of immunological status might be advisable in postmeningitic patients undergoing cochlear implantation to reduce the risk of postoperative infectious complications.

• 出版日期2012-12