摘要
A new resin glycoside, named calysolin XVIII (1), was isolated from the leaves, stems and roots of Calystegia soldanella Roem. et Schult. (Convolvulaceae). The structure of 1 was defined as 11S-jalapinolic acid 11-O-beta-D-glucopyranosyl-(1 -> 3)-O-(2-O-2S-methylbutyryl, 4-O-3-hydroxy-2-methylenebutyryl)-alpha-l-rhamnopyranosyl-(1 -> 2)-[O-beta-D-glucopyranosyl-(1 -> 6)-O-(34-di-O-2S-methylbutyryl)-beta-D-glucopyranosyl-(1 -> 3)]-O-beta-D-glucopyranosyl-(1 -> 2)-beta-D-quinovopyranoside, intramolecular 1,2 ''''''-ester on the basis of spectroscopic data. Compound 1 is the first known resin glycoside to feature 3-hydroxy-2-methylenebutyric acid as a component organic acid. In addition, 1 demonstrated an antiviral activity against herpes simplex virus type 1, with an IC50 value 2.3 mu M. [GRAPHICS] .
- 出版日期2017