Utilization of methanol in crude glycerol to assist lipid production in non-sterilized fermentation from Trichosporon oleaginosus

作者：Chen, Jiaxin; Zhang, Xiaolei; Tyagi, Rajeshwar Dayal^*; Drogui, Patrick

来源：Bioresource Technology, 2018, 253: 8-15.

DOI：10.1016/j.biortech.2018.01.008

• Lipid production
• Oleaginous yeast
• Non-sterilized fermentation
• Methanol
• Crude glycerol

In this work, methanol in crude glycerol solution was used to assist the lipid production with oleaginous yeast Trichosporon oleaginosus cultivated under non-sterilized conditions. The investigated methanol concentration was 0%, 1.4%, 2.2%, 3.3% and 4.4% (w/v). The results showed that methanol played a significant role in the non-sterilized fermentation for lipid production. The optimal methanol concentration was around 1.4% (w/v) in which the growth of T. oleaginosus was promoted and overcame that of the contaminants. The non-sterilized fed-batch fermentation with initial methanol concentration of 1.4% (w/v) was then performed and high biomass production (43.39 g/L) and lipid production (20.42 g/L) were achieved.

• 出版日期2018-4
• 单位哈尔滨工业大学