Use of Skeletal Muscle MRI in Diagnosis and Monitoring Disease Progression in Duchenne Muscular Dystrophy

作者：Finanger Erika L^*; Russman Barry; Forbes Sean C; Rooney William D; Walter Glenn A; Vandenborne Krista

来源：Physical Medicine and Rehabilitation Clinics of North America, 2012, 23(1): 1-+.

DOI：10.1016/j.pmr.2011.11.004

• MRI
• Duchenne muscular dystrophy
• Skeletal muscle

Studies have shown promise in using various approaches of magnetic resonance imaging (MRI) and magnetic resonance spectroscopy to evaluate skeletal muscle involvement in Duchenne muscular dystrophy. However, these studies have mainly been performed using a cross-sectional design, and the correlation of these MRI changes with disease progression and disease severity has not been fully elucidated. Overall, skeletal muscle MRI is a powerful and sensitive technique in the evaluation of muscle disease, and its use as a biomarker for disease progression or therapeutic response in clinical trials deserves further study.

• 出版日期2012-2