A change in nucleotide selectivity pattern of porphyrin derivatives after immobilization on gold nanoparticles

作者：Rezanka Pavel; Zaruba Kamil; Kral Vladimir^*

来源：Tetrahedron Letters, 2008, 49(45): 6448-6453.

DOI：10.1016/j.tetlet.2008.08.099

Two porphyrin-quaternized brucine salts 1 and 2 were immobilized on 3-mercaptopropanoic acid derivatized gold nanoparticles. The porphyrin modified nanoparticles were purified and characterized by a variety of techniques including electron microscopy and absorption spectroscopy in the UV-vis range. Interactions of nucleotides with 1 and 2 in solution and after immobilization of 1 and 2 on the Surface of the nanoparticles were studied. A change in the selectivity pattern towards nucleotides as an effect of the porphyrin derivative immobilization is demonstrated.

• 出版日期2008-11-3