Hepatitis B, C virus co-infection and behavioral risks in HIV-positive patients in southern Iran

作者：Zahedi Mohammad Javad; Moghaddam Sodaif Darvish^*; Abasi Mehdi Hayatbakhsh; Parnian Maryam; Shokoohi Mostafa

来源：Journal of Pakistan Medical Association, 2014, 64(2): 134-137.

• Human immunodeficiency virus
• Hepatitis virus
• Co-infection

Objective: To determine the risk factors and frequency of hepatitis B and C virus co-infections in human immunodeficiency virus-positive patients.
Methods: The cross-sectional study was conducted at the Control of Diseases Centre of Kerman Medical University, southern Iran, between May and December 2011. Demographic features and history of high-risk behaviours were evaluated in 165 patients positive for human immunodeficiency virus. Third-generation hepatitis C virus antibody and hepatitis B surface antigen tests were performed by enzyme-linked immunosorbent assay method. SPSS 18 was used for statistical analysis.
Results: Out of the 165 patients, 136(82.4%) were male and 29(17.6%) were female. The mean age of the subjects was 40.4 +/- 9 years. Positive hepatitis C antibody was found in 122 (73.9%) and positive hepatitis B surface antigen was present in 6 (3.6%). Frequency of all three viruses co-infection was 3 (1.8%). History of imprisonment (OR=17.5; 95% Cl: 7.1-43.1) and drug injection addiction (OR=15.3; 95% Cl: 6.4-36.1) were the most significant risk factors involved in hepatitis C virus co-infection.
Conclusion: Seroprevalence of hepatitis C virus and human immunodeficiency virus co-infection was high and it was strongly related to history of imprisonment and drug injection addiction.

• 出版日期2014-2