An Articulate Oxidative Transition-Metal-Free Homocoupling of Imidazo Heterocycles through C(sp(2))-C(sp(2)) Bond Formation

作者：Shakoor S M Abdul; Mandal Sanjay K; Sakhuja Rajeev^*

来源：European Journal of Organic Chemistry, 2017, 2017(18): 2596-2602.

DOI：10.1002/ejoc.201700238

• C-H activation
• Hypervalent compounds
• Homocoupling
• Nitrogen heterocycles
• Iodine reagents

Direct oxidative homocoupling of 2-arylimidazo heterocycles was achieved by using a phenyliodine diacetate-mediated BF3<bold>OEt</bold>2-accelerated protocol at room temperature. A series of biimidazo heterocycles were synthesized under ambient conditions without prior activation of the C(sp(2))-H bond. The desired biimidazo heterocycles were also obtained by using catalytic amounts of iodobenzene and m-CPBA/AcOH in an organocatalytic fashion.

• 出版日期2017-5-10