A Self-Killing Rabies Virus That Leaves a Trace on the DNA

作者:Menegas William; Uchida Naoshige; Watabe Uchida Mitsuko*
来源:Trends in Neurosciences, 2017, 40(10): 589-591.
DOI:10.1016/j.tins.2017.08.005

摘要

Although modified rabies viruses have emerged as a powerful tool for tracing the inputs to genetically defined populations of neurons, the toxicity of the virus has limited its utility. A recent study employed a self-inactivating rabies (SiR) virus that enables recording or manipulation of targeted neurons for months.

  • 出版日期2017-10