Elucidation of the biosynthesis of the di-C-glycosylflavone isoschaftoside, an allelopathic component from Desmodium spp. that inhibits Striga spp. development

作者：Hamilton Mary L; Kuate Serge P; Brazier Hicks Melissa; Caulfield John C; Rose Ruth; Edwards Robert; Torto Baldwyn; Pickett John A; Hooper Antony M^*

来源：Phytochemistry, 2012, 84: 169-176.

DOI：10.1016/j.phytochem.2012.08.005

• Desmodium uncinatum
• Desmodium intortum
• Biosynthesis
• Di-C-glycosylflavone
• C-Glycosyltransferase
• Isoschaftoside

Isoschaftoside, an allelopathic di-C-glycosylflavone from Desmodium spp. root exudates, is biosynthesised through sequential glucosylation and arabinosylation of 2-hydroxynaringenin with UDP-glucose and UDP-arabinose. Complete conversion to the flavone requires chemical dehydration implying a dehydratase enzyme has a role in vivo to complete the biosynthesis. The C-glucosyltransferase has been partially characterised and its activity demonstrated in highly purified fractions.

• 出版日期2012-12