Analysis of clinical effect of high-intensity focused ultrasound on liver cancer

作者:Li, Chuan-Xing*; Xu, Guo-Liang; Jiang, Zhen-You; Li, Jian-Jun; Luo, Guang-Yu; Shan, Hong-Bo; Zhang, Rong; Li, Yin
来源:World Journal of Gastroenterology, 2004, 10(15): 2201-2204.
DOI:10.3748/wjg.v10.i15.2201

摘要

AIM: To evaluate the clinical effect of high-intensity focused ultrasound (HIFU) in the treatment of patients with liver cancer. @@@ METHODS: HIFU treatment was performed in 100 patients with liver cancer under general anesthesia and by a targeted ultrasound. Evaluation of efficacy was made on the basis of clinical symptoms, liver function tests, AFP, MRI or CT before and after the treatment. @@@ RESULTS: After HIFU treatment, clinical symptoms were relieved in 86.6%(71/82) of patients. The ascites disappeared in 6 patients. ALT (95 +/- 44) U/L and AST (114 +/- 58) U/L before HIFU treatment were reduced to normal in 83.3%(30/36) and 72.9%(35/48) patients, respectively, after the treatment. AFP was lowered by more than 50% in 65.3%(32/49) patients. After HIFU treatment, MRI or CT findings indicated coagulation necrosis and blood supply reduction or disappearance of tumor in the target region. @@@ CONCLUSION: HIFU can efficiently treat the patients with liver cancer. It will offer a significant noninvasive therapy for local treatment of liver tumor. @@@ Li CX, Xu GL, Jiang ZY, Li JJ, Luo GY, Shan HB, Zhang R, Li Y. Analysis of clinical effect of high-intensity focused ultrasound on liver cancer. World J Gastroenterol 2004; 10(15): 2201-2204 http://www.wjgnet.com/1007-9327/10/2201.asp